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Health Aging. 21, 180–185. https://doi.org/10.1007/s12603-017-0983-3 (2017).CAS Article PubMed Google Scholar Page 2 Variables Pectoralis major Above median CSA (n = 94) Below median CSA (n = 96) P-value Age, years 78 (74, 81) 78 (74, 82) 0.70 Sex, male 56 (59.6%) 57 (60.6%) 1.00 Body mass index (kg/m2) 22.6 (20.3, 24.9) 20.7 (17.7, 22.5) < 0.01 NRS-2002 points, median (IQR) 4 (4, 7) 7 (4, 7) < 0.01 Intubation 62 (66.0%) 59 (62.1%) 0.57 Charlson comorbidity index 3 (2, 4) 2 (1, 4) 0.50 Hypertension 70 (74.5%) 65 (67.7%) 0.34 Diabetes 49 (52.1%) 43 (43.8%) 0.38 Congestive heart failure 10 (10.6%) 9 (9.4%) 0.81 Chronic renal failure 34 (26.2%) 29 (30.2%) 0.44 Chronic obstructive lung disease 11 (11.7%) 11 (11.5%) 1.00 Cancer 16 (17%) 24 (25.0%) 0.21 Reason for ICU admission Respiratory failure 40 (42.6%) 53 (55.2%) 0.08 Non-respiratory sepsis 27 (28.7%) 25 (26.0%) 0.75 Hemorrhagic shock 4 (4.3%) 2 (2.1%) 0.44 Altered mental status 12 (12.8%) 2 (2.1%) 0.01 Metabolic cause 7 (7.4%) 7 (7.3%) 1.00 Cardiovascular 4 (4.3%) 0 (0.0%) 0.06 Other 0 (0.0%) 7 (7.3%) 0.01 SOFA score at ICU admission, median (IQR) 6 (4, 11) 8 (6, 10) 0.40 Prolonged mechanical ventilation, n (%)* 10/47 (21.3%) 17/40 (42.5%) 0.03 ICU days, median (IQR) 8 (3, 14) 6 (3, 12) 0.59 ICU death, n (%) 15 (16.0%) 28 (29.2%) 0.04 Hospital days, median (IQR) 20.5 (14, 38) 19.5 (12, 41) 0.67 Hospital death, n (%) 26 (27.7%) 45 (46.9%) 0.01 Continuous variables are presented as median (interquartile range) and categorical variables are presented as numbers (percentage). CSA Cross-sectional area, ICU intensive care unit, SOFA sequential organ failure assessment. Cutoff values for lower half in pectoralis muscles are 26.5 cm2 in men, and 18.3 cm2 in women, respectively.
https://www.nature.com/articles/s41598-021-02853-4
Thoracic skeletal muscle quantification using computed tomography and prognosis of elderly ICU patients
