A Researcher or Senior Researcher position is available in the laboratory of Dr. Myriam Labelle in the Department of Developmental Neurobiology at St. Jude Children’s Research Hospital. The Labelle laboratory studies the role of the microenvironment in cancer progression and metastasis, with major efforts dedicated to elucidating the molecular mechanisms by which blood platelets, granulocytes, and the extracellular matrix (ECM) cooperate to promote metastasis (Labelle et al.,Cancer Cell, 2011; PNAS, 2014). In recent work (Hong et al. EMBO J, 2019), we discovered that WISP1, a factor secreted by tumor cells upon interactions with platelets, promotes metastasis by inducing collagen linearization in tumors. Current studies are conducted leveraging a wide array of model systems and techniques including novel mouse models of metastasis, patient-derived xenografts, in vitro co-culture systems, and advanced microscopy approaches.
We are looking for a highly motivated, responsible and organized individual to carry out experimental research and help maintain efficient laboratory operations. Work in the lab involves a large number of approaches including work with murine models, tissue culture, microscopy, molecular biology, genetics and biochemistry.
https://www.nature.com/naturecareers/job/researchersenior-researcher-in-cancer-progression-and-metastasis-st-jude-childrens-research-hospital-st-jude-748995
