If there’s one pandemic fact that has been proved beyond a doubt, it’s that a virus can spread faster than the news. And in this digital world, where headlines leap borders in a moment, that’s an alarming development to keep in mind for the future.
Today, as Americans were waking up for their Black Friday rituals, they were greeted with the news that a new mutation of the Covid-19 virus has appeared — after it caught an international flight to Hong Kong.
The variant is now tagged as B.1.1.529.
Here’s what we know.
Over the past 48 hours health officials spotted the new variant as it spurred an increase in infections around Johannesburg.
‘This variant did surprise us — it has a big jump in evolution, many more mutations than we expected, especially after a very severe third wave of Delta,’ said Tulio de Oliveira, director of the KwaZulu-Natal Research and Innovation Sequencing Platform, according to a report in The New York Times.
‘The sequence of this variant, currently called B.1.1.529, was first uploaded by Hong Kong from a case of someone traveling from South Africa,’ the British health minister, Sajid Javid, said. ‘The UK was the first country to identify the potential threat of this new variant and to alert international partners. Further cases have been identified in South Africa and in Botswana, and it is highly likely that it has now spread to other countries.’
Israeli officials also report that one case has been confirmed in a traveler returning from Malawi. Two other suspected cases are being studied now. All 3 were already vaccinated against Covid-19.
European health officials, already grappling with a lethal spike in infections from the Delta variant, started slapping on travel restrictions that began mid-day Friday, European time.
COVID-19 UPDATE:@UKHSA is investigating a new variant. More data is needed but we’re taking precautions now.
From noon tomorrow six African countries will be added to the red list, flights will be temporarily banned, and UK travellers must quarantine.
— Sajid Javid (@sajidjavid) November 25, 2021 All of Europe is expected to follow soon, with Japan and others already taking action.
The @EU_Commission will propose, in close coordination with Member States, to activate the emergency brake to stop air travel from the southern African region due to the variant of concern B.1.1.529.
— Ursula von der Leyen (@vonderleyen) November 26, 2021 Next steps will entail studying this mutation to determine just what kind of threat it presents and whether the current vaccines in use can protect everyone that’s been vaccinated already.
It also underscores the new normal for this world, as countries continue to push for wider vaccination to end a pandemic that continues to bedevil the world close to 2 years after Covid-19 began to rattle the globe. The world has now become a breeding ground of new viral mutations. And there’s no end in sight.
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A nonprofit dedicated to transparency is calling on the FDA to release any and all documentation related to the approval of the Pfizer/BioNTech Covid-19 vaccine. And while FOIA requests are notorious for taking months if not years to fulfill, this time the FDA is asking for 55 years to complete the request.
After the FDA denied expediting the group’s FOIA request, the nonprofit sued FDA in the US District Court in northern Texas, attempting to compel the agency to expedite their request, which was that FDA turn over about 329,000 pages of documents in less than 3 months.
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The FDA has slapped a clinical hold on the early-stage program for one of Kura Oncology’s cancer drugs following a patient’s death in a clinical trial.
The biotech $KURA reported early Wednesday that the Phase Ib study of KO-539 for acute myeloid leukemia would be halted, suspending enrollment, while researchers and the FDA probed the death. Patients already on the drug can continue taking it.
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Forget the migraine marketing brand wars. When it comes to patients, many can’t even name one despite substantial advertising efforts, according to a new study from Phreesia that concludes CGRP migraine drugmakers still need to work on brand recognition.
Almost half (47%) of the patients Phreesia surveyed couldn’t name one preventative migraine brand. The best performer was Topamax, a small molecule anticonvulsant that’s been around since 2004, which 26% of migraine patients could recall. Among the new CGRP brand names recognized, Amgen’s Aimovig ranked highest with 8% recall, while Eli Lilly’s Emgality and Biohaven’s Nurtec tied at 7% and Teva’s Ajovy was remembered by 3% of patients.
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Emma Walmsley, GlaxoSmithKline CEO (Fang Zhe/Xinhua/Alamy Live News)
As activist investors champ at the bit for change at drug giant GlaxoSmithKline, the pharma giant has turned over many rocks to find an R&D success to present to its detractors. In NASH, a field strewn with failures, GSK hopes a new license deal can churn out a much-needed winner.
GSK will pay $120 million in upfront cash and $910 million in downstream milestones to develop and sell ARO-HSD, Arrowhead Pharmaceuticals’ RNA interference drug targeting fatty liver disease nonalcoholic steatohepatitis (NASH), the companies said Monday.
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Amidst a push to ease pressure on the supply chain domestically, BD Biosciences will expand at the San Diego Reagent Innovation Center, as the property developer announced the company’s plans Monday.
The San Diego site will be at Torrey View, a 10-acre life sciences R&D campus that Breakthrough Properties is creating alongside Mitsui Fudosan America. It’s within the life sciences cluster of Del Mar Heights, which offers nearby housing for employees in biopharma.
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Ursula von der Leyen (Christian Hartmann/Pool Photo via AP Images)
Pfizer is suing its former associate director of clinical statistics in a California court after she uploaded thousands of files to her personal Google drive in October and then misled the company about what she took and where the files are today.
According to the complaint filed Tuesday evening, Chun Xiao (Sherry) Li uploaded over 12,000 files — including scores of confidential Pfizer documents — from her Pfizer-issued laptop to a personal account and when Pfizer addressed the issue with her, she initially gave the appearance of cooperation, but instead misled Pfizer about what she took, how she took it, when and why she did it.
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Robert Califf (Pablo Martinez Monsivais, AP Images)
President Biden’s nominee to run the FDA was hit with some tepid criticism back in 2016 for being too cozy with the biopharma industry because some of the trials he ran had industry sponsors and some of the funding he took was from industry.
Nevertheless, Rob Califf sailed through his confirmation then, and his successor Scott Gottlieb showed that even closer ties to industry shouldn’t stop an effective leader from being FDA commissioner.
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Most people know if they’re ‘Team Pfizer’ or ‘Team Moderna,’ but few know if they got the Comirnaty or Spikevax Covid-19 vaccine. Those are the brand names of Pfizer and Moderna vaccines, respectively, however they have yet to take hold with consumers, media or even medical professionals.
And there are others. Covid vaccine brand names also include AstraZeneca’s Vaxzevria, Novavax’s Nuvaxovid, and Sanofi and GlaxoSmithKline’s Vidprevtyn. J&J’s Janssen-developed Covid vaccine is the lone major holdout and is still yet to be named, if ever. In EMA filings approving its conditional use, the brand name is listed simply as ‘Covid-19 Vaccine Janssen.’
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https://endpts.com/new-coronavirus-mutation-takes-flight-around-the-globe-as-health-officials-scramble-to-mount-new-defenses/